Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | KCNJ6 | P48051 | 5/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23399290 | 0.85 | KCNJ6 (0.50) | ALDH1A1GAAMAPK13MAPK12MAPK11 | |
| SCHEMBL20681363 | 0.82 | ALDH1A1 (0.62) | ALDH1A1GAAMAPK13MAPK12MAPK11 | |
| SCHEMBL23400493 | 0.82 | KCNJ6 (0.50) | ALDH1A1GAAMAPK13MAPK12MAPK11 | |
| SCHEMBL12385633 | 0.81 | ALDH1A1 (0.60) | ALDH1A1GAAMAPK13MAPK12MAPK11 | |
| SCHEMBL1012992 | 0.79 | CYP1A2 (0.62) | ALDH1A1GAAMAPK13MAPK12MAPK11 | |
| SCHEMBL23398657 | 0.79 | ALDH1A1 (0.45) | ALDH1A1GAAMAPK13MAPK12MAPK11 | |
| SCHEMBL23399292 | 0.79 | ALDH1A1 (0.43) | ALDH1A1GAAMAPK13MAPK12MAPK11 | |
| SCHEMBL4498910 | 0.79 | ALDH1A1 (1.00) | ALDH1A1GAAMAPK13MAPK12MAPK11 | |
| SCHEMBL13221532 | 0.79 | ALDH1A1 (0.58) | ALDH1A1GAAMAPK13MAPK12MAPK11 | |
| SCHEMBL16770394 | 0.78 | ALDH1A1 (0.42) | ALDH1A1GAAMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930520-A | N-aryl pyrazole compound, and pharmaceutical composition and application thereof | 中国药科大学 | 2025-05-06 | — | — | CN | disclosed |
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |
| US-20210079017-A1 | NEPRILYSIN INHIBITORS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2021-03-18 | — | — | US | disclosed |
| US-9682938-B2 | Pyrazolone derivatives as nitroxyl donors | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| EP-3148972-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | Cardioxyl Pharmaceuticals Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015183839-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2015-12-03 | — | — | WO | disclosed |
| US-20150344437-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | THE JOHNS HOPKINS UNIVERSITY | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344437-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | TNNI3, PFKP, NOX5 | ALDH1A1 1883/4885GAA 1354/4885MAPK13 3571/4885 |
| US-20210079017-A1 | NEPRILYSIN INHIBITORS | MME, REN, ACE | ALDH1A1 2644/4885GAA 125/4885MAPK13 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.