SCHEMBL1729127

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17291956	0.82	PTGDR2 (0.35)	PTGDR2ALDH1A1KDM4ECYP1A2
	SCHEMBL1729069	0.78	ALDH1A1 (0.41)	PTGDR2ALDH1A1CYP1A2LMNA
	SCHEMBL1729169	0.78	PTGDR2 (0.35)	PTGDR2ALDH1A1CYP1A2MAPTSMN1; SMN2
	SCHEMBL8807107	0.78	ALDH1A1 (0.39)	ALOX15ALDH1A1KDM4ECYP1A2MAPT
	SCHEMBL6920738	0.77	PTGDR2 (0.32)	PTGDR2
	SCHEMBL28734927	0.72	CA2 (0.46)	ALDH1A1KDM4ECYP1A2MAPTCYP3A4
	SCHEMBL6033258	0.72	ALDH1A1 (0.36)	ALDH1A1CYP1A2EGFRCYP2C9
	SCHEMBL5086986	0.72	CYP2D6 (0.38)	ALDH1A1KDM4ECYP1A2MAPTSMN1; SMN2
	SCHEMBL28734957	0.71	HTR2A (0.30)	—
	SCHEMBL8779698	0.71	EGFR (0.48)	ALDH1A1KDM4EMAPTLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.