SCHEMBL5086986

SCHEMBL5086986

COCOc1c(Br)cc(C)cc1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.38
CYP3A4 P08684 1/20 0.38
ALDH1A1 P00352 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CA2 P00918 1/20 0.37
POLB P06746 1/20 0.37
TYR P14679 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 5/20 0.35
MAPT P10636 4/20 0.35
HSPA5 P11021 1/20 0.35
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
HIF1A Q16665 2/20 0.34
LMNA P02545 3/20 0.34
KDM4E B2RXH2 5/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 1/20 0.33
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30746816 0.88 MEN1 (0.34) CYP2D6ALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL22321054 0.88 MEN1 (0.34) CYP2D6ALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL25925320 0.86 L3MBTL1 (0.39) CYP2D6CYP3A4ALDH1A1SMN1; SMN2CA2
SCHEMBL25402814 0.84 KMT2A (0.46) CYP2D6ALDH1A1SMN1; SMN2CA2MEN1
SCHEMBL6033258 0.83 ALDH1A1 (0.36) CYP2D6ALDH1A1CYP2C9CYP2C19HIF1A
SCHEMBL28734927 0.83 CA2 (0.46) CYP3A4ALDH1A1CA2MEN1KMT2A
SCHEMBL23774990 0.83 SMN1; SMN2 (0.39) CYP2D6CYP3A4ALDH1A1SMN1; SMN2CA2
SCHEMBL28734957 0.82 HTR2A (0.30)
SCHEMBL1627319 0.80 CA2 (0.43) CYP2D6CYP3A4ALDH1A1SMN1; SMN2CA2
SCHEMBL26624872 0.80 CYP2D6 (0.38) CYP2D6CYP3A4ALDH1A1SMN1; SMN2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115427464-B Lewis base catalyst and method thereof 埃克森美孚化学专利公司 2024-10-29 CN disclosed
US-11732063-B2 Lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-22 US disclosed
CN-113423744-B Lewis base catalyst and method thereof 埃克森美孚化学专利公司 2023-05-05 CN disclosed
CN-113423742-B Bis (arylphenoxide) lewis base catalysts and methods thereof 埃克森美孚化学专利公司 2023-05-05 CN disclosed
CN-115427464-A Lewis base catalyst and process therefor 埃克森美孚化学专利公司 2022-12-02 CN disclosed
US-11248070-B2 Lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-02-15 US disclosed
US-11248070-B2 Lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-02-15 US disclosed
US-11214634-B2 Lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-01-04 US disclosed
US-11214634-B2 Lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-01-04 US disclosed
EP-3924395-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF ExxonMobil Chemical Patents Inc. (US) 2021-12-22 EP disclosed
CN-1080724-C Transition metal complexes, catalyst for olefin polymerization, and process for producing olefin polymers SUMITOMO CHEMICAL CO (JP) 2002-03-13 CN disclosed
US-6329478-B1 SOLUBILITY IN SATURATED HYDROCARBON SOLVENTS SUMITMO CHEMICAL COMPANY, LIMITED 2001-12-11 US disclosed
EP-0852230-B1 TRANSITION METAL COMPLEXES, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL CO (JP) 2001-12-05 EP disclosed
CN-1310183-A Transition metal compound, its producing process olefine polymerization catalyst containing the same transition metal compound and process for producing olefine polymer SUMITOMO CHEMICAL CO (JP) 2001-08-29 CN disclosed
CN-1068884-C Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex, and process for producing olefin polymer SUMITOMO CHEM IND (JP) 2001-07-25 CN disclosed
US-6066704-A Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-23 US disclosed
CN-1194650-A Transition metal complexes, catalyst for olefin polymerization, and process for producing olefin polymers SUMITOMO CHEMICAL CO (JP) 1998-09-30 CN disclosed
CN-1193323-A Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex, and process for producing olefin polymer SUMITOMO CHEM IND (JP) 1998-09-16 CN disclosed
EP-0852230-A1 TRANSITION METAL COMPLEXES, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-07-08 EP disclosed
EP-0842939-A1 TRANSITION METAL COMPLEX, PROCESS FOR THE PREPARATION THEREOF, POLYMERIZATION CATALYST FOR OLEFINS CONTAINING THE COMPLEX, AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11732063-B2 Lewis base catalysts and methods thereof TEC, ALOX12, ELL CYP2D6 1281/4885CYP3A4 1531/4885ALDH1A1 2743/4885
US-11214634-B2 Lewis base catalysts and methods thereof ELL, PHKB, POLI CYP2D6 3839/4885CYP3A4 3515/4885ALDH1A1 2198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.