Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728824 | 0.80 | POLB (0.67) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL3266144 | 0.79 | POLB (0.57) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1729003 | 0.76 | PKM (0.48) | ALDH1A1KMT2APKM | |
| SCHEMBL1729364 | 0.75 | KMT2A (0.50) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14559593 | 0.72 | POLB (0.67) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4166695 | 0.72 | MEN1 (0.60) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1729366 | 0.71 | MAPT (0.47) | POLBALDH1A1MEN1KMT2AMAPT | |
| Bromide SCHEMBL4174809 | 0.71 | MEN1 (0.59) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL3075661 | 0.71 | CNR2 (0.67) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1727889 | 0.70 | HTR2A (0.51) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |