Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727882 | 0.84 | DRD2 (0.55) | HTR2AHTR2CHTR7DRD2DRD4 | |
| SCHEMBL1727831 | 0.77 | FAAH (0.47) | — | |
| SCHEMBL1728045 | 0.77 | DRD2 (0.52) | HTR2AHTR2CHTR7DRD2DRD4 | |
| SCHEMBL8273476 | 0.75 | MEN1 (0.64) | LMNAGFER | |
| Fumaric Acid SCHEMBL10704726 | 0.73 | KCNH2 (0.52) | HTR2AHTR7DRD2DRD4KCNH2 | |
| SCHEMBL3054073 | 0.71 | KCNH2 (0.56) | HTR7DRD2KCNH2SIGMAR1CYP2D6 | |
| SCHEMBL11338189 | 0.71 | HTR1A (0.65) | HTR2AHTR2CHTR2BHTR7DRD2 | |
| SCHEMBL10678137 | 0.71 | KCNH2 (0.65) | HTR2AHTR7DRD2KCNH2OPRM1 | |
| SCHEMBL12150894 | 0.71 | HTR1A (0.66) | HTR7LMNAHTR1A | |
| SCHEMBL5988317 | 0.71 | KCNH2 (0.88) | HTR2ADRD2KCNH2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |