Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729289 | 0.90 | P4HTM (0.38) | P4HTMEGLN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1728046 | 0.78 | NPC1 (0.49) | CYP1A2HSD17B10HRH4TSHRKDM4E | |
| SCHEMBL1728003 | 0.77 | CD38 (0.43) | P4HTMEGLN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1728910 | 0.76 | CHRM4 (0.44) | P4HTMEGLN2NOS2HCRTR2CYP2C9 | |
| SCHEMBL1729295 | 0.76 | P4HTM (0.37) | P4HTMEGLN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3266167 | 0.75 | NOS2 (0.38) | P4HTMEGLN2NOS2CHEK1CHEK2 | |
| SCHEMBL3265541 | 0.74 | SIRT2 (0.41) | P4HTMEGLN2NOS2CHEK1CHEK2 | |
| SCHEMBL1729035 | 0.72 | FFAR4 (0.37) | CYP3A4 | |
| SCHEMBL1727687 | 0.71 | PDE10A (0.43) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL1730318 | 0.71 | HRH3 (0.43) | KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |