Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.39 |
| ▸ | ITGAL | P20701 | 3/20 | 0.39 |
| ▸ | CKS1B | P61024 | 5/20 | 0.38 |
| ▸ | SKP1 | P63208 | 5/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727769 | 0.83 | CHRNA7 (0.43) | NPC1TSHRRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1727912 | 0.83 | CNR1 (0.42) | CKS1BSKP1SKP2PKM | |
| SCHEMBL1730046 | 0.80 | DKK1 (0.49) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1729376 | 0.78 | P4HTM (0.39) | TSHRSMN1; SMN2HRH4KDM4EALDH1A1 | |
| SCHEMBL1727885 | 0.76 | KDM4E (0.41) | TSHRRECQLKDM4EALDH1A1MAPT | |
| SCHEMBL1729041 | 0.76 | NPC1 (0.55) | NPC1TSHRRECQLRAB9ASMN1; SMN2 | |
| SCHEMBL1729255 | 0.76 | HTR1A (0.43) | NPC1RAB9ASMN1; SMN2CKS1BSKP1 | |
| SCHEMBL3268917 | 0.75 | CKS1B (0.47) | NPC1TSHRRECQLRAB9ASMN1; SMN2 | |
| SCHEMBL1728042 | 0.75 | RXRA (0.46) | ITGB2ICAM1ITGALCKS1BSKP1 | |
| SCHEMBL1727687 | 0.74 | PDE10A (0.43) | SMN1; SMN2CKS1BSKP1SKP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |