Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 3/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 4/20 | 0.39 |
| ▸ | SKP1 | P63208 | 4/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728910 | 0.89 | CHRM4 (0.44) | CD38P4HTMNOS2EGLN2 | |
| SCHEMBL3266167 | 0.84 | NOS2 (0.38) | CD38P4HTMNOS2NAPEPLDEGLN2 | |
| SCHEMBL27920414 | 0.77 | GPR119 (0.48) | CKS1BSKP1SKP2CYP3A4CYP2D6 | |
| SCHEMBL1729376 | 0.77 | P4HTM (0.39) | P4HTMNOS2NAPEPLDEGLN2CYP1A2 | |
| SCHEMBL13736723 | 0.77 | CKS1B (0.41) | CKS1BSKP1SKP2HSD17B10CHEK1 | |
| SCHEMBL3265541 | 0.76 | SIRT2 (0.41) | CD38P4HTMNOS2EGLN2CHEK1 | |
| SCHEMBL1729289 | 0.76 | P4HTM (0.38) | P4HTMNOS2NAPEPLDEGLN2CYP1A2 | |
| SCHEMBL1729041 | 0.75 | NPC1 (0.55) | CKS1BSKP1SKP2TSHR | |
| SCHEMBL5722152 | 0.73 | NOS2 (0.52) | NOS2 | |
| SCHEMBL1774210 | 0.72 | LOXL2 (0.41) | CKS1BSKP1SKP2HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |