Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CKS1B | P61024 | 2/20 | 0.48 |
| ▸ | SKP1 | P63208 | 2/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728821 | 0.90 | CHRM4 (0.68) | FFAR4CHRM4ADRB1FFAR1HRH3 | |
| SCHEMBL3265679 | 0.83 | CHRM4 (0.50) | FFAR4CHRM4ADRB1FFAR1HRH3 | |
| SCHEMBL1728740 | 0.82 | LMNA (0.61) | CHRM4CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL2005045 | 0.82 | FFAR4 (0.56) | FFAR4CHRM4ADRB1FFAR1HRH3 | |
| SCHEMBL31537419 | 0.81 | ADRB1 (0.63) | FFAR4CHRM4ADRB1FFAR1HRH3 | |
| SCHEMBL3928983 | 0.81 | FFAR4 (0.55) | FFAR4CHRM4ADRB1FFAR1HRH3 | |
| SCHEMBL7130750 | 0.79 | ADRB1 (0.59) | FFAR4CHRM4ADRB1FFAR1HRH3 | |
| SCHEMBL22776419 | 0.78 | ALDH1A1 (0.52) | KDM4EALDH1A1CKS1BSKP1SKP2 | |
| SCHEMBL1728756 | 0.77 | CHRM4 (0.59) | CHRM4ADRB1CETPCHRM2CHRM3 | |
| SCHEMBL7134998 | 0.77 | KDM4E (0.67) | FFAR4CHRM4ADRB1FFAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |