Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729132 | 0.88 | DRD4 (0.52) | DRD4MGLLMAPTEGLN1DRD2 | |
| SCHEMBL1727411 | 0.85 | DRD4 (0.47) | DRD4KMT2AEGLN1ALDH1A1DRD2 | |
| SCHEMBL1728732 | 0.85 | DRD4 (0.62) | DRD4MAPTEGLN1DRD2DRD3 | |
| SCHEMBL2329208 | 0.84 | CNR2 (0.54) | CNR2MGLLEGLN1 | |
| SCHEMBL1728735 | 0.82 | DRD4 (0.49) | DRD4DYRK1AHTR2ASLC6A4HTR1A | |
| SCHEMBL1727657 | 0.82 | CNR1 (0.54) | MAPTPOLBKMT2APKMALDH1A1 | |
| SCHEMBL1727732 | 0.79 | CD274 (0.50) | DRD4EGLN1HTR2ASLC6A4HTR1A | |
| SCHEMBL1729537 | 0.79 | DRD4 (0.55) | DRD4POLBEGLN1LMNA | |
| SCHEMBL1727880 | 0.79 | CNR2 (0.50) | CNR2DRD4MGLLKMT2AEGLN1 | |
| SCHEMBL1729825 | 0.78 | CNR2 (0.47) | CNR2DRD4MGLLEGLN1DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |