Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728732 | 0.89 | DRD4 (0.62) | DRD4EGLN1 | |
| SCHEMBL1727526 | 0.86 | HRH2 (0.47) | DRD4ACHEFAAHPPARA | |
| SCHEMBL1729132 | 0.85 | DRD4 (0.52) | DRD4EGLN1 | |
| SCHEMBL1727732 | 0.83 | CD274 (0.50) | DRD4CD274EGLN1 | |
| SCHEMBL1728049 | 0.81 | DRD4 (0.51) | DRD4ACHEFAAHPOLBLMNA | |
| SCHEMBL31589961 | 0.79 | EGLN1 (0.55) | EGLN1LMNASMN1; SMN2 | |
| SCHEMBL1729393 | 0.79 | CNR2 (0.56) | DRD4EGLN1POLBLMNA | |
| SCHEMBL1728735 | 0.78 | DRD4 (0.49) | DRD4 | |
| SCHEMBL1729043 | 0.78 | EGLN1 (0.41) | DRD4ACHEEGLN1PPARA | |
| SCHEMBL1727895 | 0.78 | EGLN1 (0.43) | DRD4EGLN1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |