Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727526 | 0.89 | HRH2 (0.47) | DRD4CHRM4CHRM2CHRM1HTR1A | |
| SCHEMBL1728732 | 0.88 | DRD4 (0.62) | DRD4DRD3 | |
| SCHEMBL15662183 | 0.86 | CHRM4 (0.56) | CHRM4CHRM2CHRM1PDE4APDE4B | |
| SCHEMBL1727394 | 0.84 | HTR1A (0.46) | DRD4SLC6A7ABL1PIM1CHRM4 | |
| SCHEMBL1729393 | 0.82 | CNR2 (0.56) | DRD4DYRK1AHTR1AHTR2ASLC6A4 | |
| SCHEMBL1728819 | 0.81 | SLC6A7 (0.43) | DRD4GRIN1GRIN2BSLC6A7PIM1 | |
| SCHEMBL1729203 | 0.81 | GRIN1 (0.42) | DRD4GRIN1GRIN2BSLC6A7PIM1 | |
| SCHEMBL1727411 | 0.80 | DRD4 (0.47) | DRD4SLC6A7CHRM4HTR1AHTR2A | |
| SCHEMBL1729537 | 0.78 | DRD4 (0.55) | DRD4 | |
| SCHEMBL1727631 | 0.78 | HTR1A (0.48) | DRD4ABL1CHRM4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |