Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.55 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450867 | 0.89 | CYP4F2 (0.55) | CYP4F2CYP4A11STING1KMT2AMEN1 | |
| SCHEMBL16294204 | 0.87 | ALOX5 (0.54) | KMT2AMEN1ALOX5OR51E2LMNA | |
| SCHEMBL491276 | 0.87 | CYP4F2 (0.59) | CYP4F2CYP4A11KMT2AMEN1DRD2 | |
| SCHEMBL8984891 | 0.85 | CYP4F2 (0.58) | CYP4F2CYP4A11KMT2ADRD2ALOX5 | |
| SCHEMBL31053236 | 0.85 | ABL1 (0.56) | STING1KMT2AMEN1DRD2ALOX5 | |
| SCHEMBL15056738 | 0.85 | ABL1 (0.56) | STING1KMT2AMEN1DRD2ALOX5 | |
| SCHEMBL8912630 | 0.85 | CYP4F2 (0.58) | CYP4F2CYP4A11KMT2ADRD2ALOX5 | |
| Dihydroferulic Acid Ethyl Ester SCHEMBL356300 | 0.84 | ALOX5 (0.67) | CYP4F2CYP4A11ALOX5OR51E2LMNA | |
| SCHEMBL31236982 | 0.84 | ALDH1A1 (0.42) | STING1KMT2AMEN1DRD2LMNA | |
| SCHEMBL4167602 | 0.83 | CYP4F2 (0.55) | CYP4F2CYP4A11ALOX5OR51E2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181272-A1 | RAB GERANYLGERANYL TRANSFERASE INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015181272-A1 | RAB GERANYLGERANYL TRANSFERASE INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2015-12-03 | — | — | WO | disclosed |