Dihydroferulic Acid Ethyl Ester

Dihydroferulic Acid Ethyl Ester

SCHEMBL356300

CCOC(=O)CCc1ccc(O)c(OC)c1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.67
OR51E2 Q9H255 1/20 0.67
CYP1A2 P05177 3/20 0.61
CYP3A4 P08684 3/20 0.61
CYP2C8 P10632 3/20 0.61
CYP2C9 P11712 3/20 0.61
CYP2B6 P20813 3/20 0.61
CYP2C19 P33261 3/20 0.61
TAAR1 Q96RJ0 2/20 0.58
TSHR P16473 2/20 0.58
MAPK1 P28482 1/20 0.58
CYP4F2 P78329 1/20 0.56
CYP4A11 Q02928 1/20 0.56
LMNA P02545 1/20 0.56
GLA P06280 1/20 0.56
HTR1A P08908 3/20 0.56
LTA4H P09960 2/20 0.56
TRPV1 Q8NER1 2/20 0.56
CYP2E1 P05181 1/20 0.56
CYP2D6 P10635 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6583008 0.90 ALOX5 (0.62) ALOX5OR51E2CYP1A2CYP3A4CYP2C8
SCHEMBL4007566 0.89 ALOX5 (0.77) ALOX5OR51E2CYP1A2CYP3A4CYP2C8
Dihydroferulic Acid Propyl Ester SCHEMBL22353585 0.89 ALOX5 (0.63) ALOX5OR51E2CYP1A2CYP3A4CYP2C8
SCHEMBL1550337 0.88 CYP4F2 (0.56) ALOX5OR51E2CYP1A2CYP3A4CYP2C8
SCHEMBL491225 0.88 CYP19A1 (0.60) ALOX5OR51E2CYP1A2CYP3A4CYP2C8
SCHEMBL491276 0.88 CYP4F2 (0.59) CYP1A2CYP3A4CYP4F2CYP4A11LMNA
SCHEMBL16661623 0.87 ALOX5 (0.65) ALOX5OR51E2CYP1A2CYP3A4CYP2C8
SCHEMBL16661624 0.87 ALOX5 (0.65) ALOX5OR51E2CYP1A2CYP3A4CYP2C8
SCHEMBL8912630 0.87 CYP4F2 (0.58) ALOX5OR51E2CYP1A2CYP3A4CYP2C8
Dihydroferulic Acid Methyl Ester SCHEMBL490876 0.86 ALOX5 (0.77) ALOX5OR51E2CYP1A2CYP3A4CYP2C8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350133-A Method for preparing 4-propyl eugenol by catalyzing lignin to hydrogenolysis through cobalt-nitrogen co-doped porous carbon 华南理工大学 2025-01-24 CN claimed
CN-119350133-A Method for preparing 4-propyl eugenol by catalyzing lignin to hydrogenolysis through cobalt-nitrogen co-doped porous carbon 华南理工大学 2025-01-24 CN disclosed
CN-109310796-B Absorbent article comprising cyclodextrin complex 宝洁公司 2021-10-15 CN disclosed
EP-2925755-B1 NEUROPROTECTIVE AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES UNIV WAYNE STATE (US) 2021-09-08 EP disclosed
CN-109219453-B Absorbent article comprising cyclodextrin complex 宝洁公司 2021-07-06 CN disclosed
US-10874669-B2 Neuroprotective agents for treatment of neurodegenerative diseases WAYNE STATE UNIVERSITY (US) 2020-12-29 US disclosed
EP-2595952-B1 AGONISTS OF GPR40 CONNEXIOS LIFE SCIENCES PVT LTD (IN) 2020-11-18 EP disclosed
US-20200317593-A1 LIGNIN CONVERSION TO PHENOLIC MOLECULES USING TRANSITION METAL CATALYSTS SPERO RENEWABLES, LLC 2020-10-08 US disclosed
EP-3717496-A1 LIGNIN CONVERSION TO PHENOLIC MOLECULES USING TRANSITION METAL CATALYSTS Spero Renewables, LLC (US) 2020-10-07 EP disclosed
CN-106999406-B Anhydrous cosmetic composition for topical application 宝洁公司 2020-09-08 CN disclosed
US-5962695-A ANTICOAGULANT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1999-10-05 US disclosed
US-5866577-A AN ANTICOAGULANT AGENT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1999-02-02 US disclosed
WO-1998029407-A2 N-(PYRIDINYLAMINO)ISOINDOLINES FOR TREATING ALZHEIMER'S AND DEPRESSION HOECHST MARION ROUSSEL, INC. (US) 1998-07-09 WO disclosed
CN-1168886-A Process for production of amidinobenzofuran and amidionbenzothiophen derivatives and salt thereof DAIICHI SEIYAKU CO (JP) 1997-12-31 CN disclosed
CN-1168885-A Process for prodn. of amidinoindole derivatives and salts thereof DAIICHI SEIYAKU CO (JP) 1997-12-31 CN disclosed
US-5620991-A ANTICOAGULANTS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1997-04-15 US disclosed
US-5576343-A ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1996-11-19 US disclosed
EP-0540051-B1 Aromatic amidine derivatives and salts thereof DAIICHI SEIYAKU CO (JP) 1996-04-03 EP disclosed
CN-1072677-A Aromatic amidine derivative and salt thereof DAIICHI SEIYAKU CO (JP) 1993-06-02 CN disclosed
EP-0540051-A1 Aromatic amidine derivatives and salts thereof DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-05-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10874669-B2 Neuroprotective agents for treatment of neurodegenerative diseases SMN1; SMN2, PARK7, SNCA ALOX5 3375/4885OR51E2 3221/4885CYP1A2 3835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.