Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 15/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.57 |
| ▸ | ACP1 | P24666 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295403 | 1.00 | CA9 (0.60) | CA9CA2PTPN1ACP1 | |
| SCHEMBL17295441 | 0.89 | LMNA (0.49) | CA9CA2PTPN1ACP1 | |
| SCHEMBL17295442 | 0.89 | LMNA (0.49) | CA9CA2PTPN1ACP1 | |
| SCHEMBL17295528 | 0.89 | ALDH1A1 (0.62) | CA9CA2PTPN1ACP1 | |
| SCHEMBL17295526 | 0.89 | ALDH1A1 (0.62) | CA9CA2PTPN1ACP1 | |
| SCHEMBL17295388 | 0.88 | FAAH (0.62) | CA9CA2PTPN1ACP1 | |
| SCHEMBL17302192 | 0.88 | FAAH (0.62) | CA9CA2PTPN1ACP1 | |
| SCHEMBL17295632 | 0.86 | LMNA (0.57) | CA9CA2PTPN1 | |
| SCHEMBL17295631 | 0.86 | LMNA (0.57) | CA9CA2PTPN1 | |
| SCHEMBL17302139 | 0.83 | MEN1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148990-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015181337-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2015-12-03 | — | — | WO | disclosed |