SCHEMBL1729565

SCHEMBL1729565

O=S(=O)(O)c1ccc2c3c(cccc13)CC2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.58
KDM4E B2RXH2 8/20 0.58
LMNA P02545 4/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
HPGD P15428 5/20 0.54
HSD17B10 Q99714 2/20 0.54
AURKA O14965 1/20 0.51
AURKB Q96GD4 1/20 0.51
TTR P02766 1/20 0.50
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
MAPT P10636 4/20 0.48
GAA P10253 3/20 0.48
POLB P06746 3/20 0.46
CYP3A4 P08684 2/20 0.46
ALOX15 P16050 1/20 0.46
ATM Q13315 1/20 0.45
HTT P42858 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CYP1A2 P05177 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11422536 0.98 ALDH1A1 (0.56) ALDH1A1KDM4ELMNASMN1; SMN2HPGD
SCHEMBL1108433 0.81 ALDH1A1 (0.58) ALDH1A1KDM4ELMNASMN1; SMN2HPGD
SCHEMBL11422534 0.80 ALDH1A1 (0.56) ALDH1A1KDM4ELMNASMN1; SMN2HPGD
SCHEMBL11436403 0.78 KDM4E (0.48) ALDH1A1KDM4ELMNASMN1; SMN2HPGD
SCHEMBL9568545 0.76 AURKB (0.58) ALDH1A1HSD17B10AURKAAURKBTTR
SCHEMBL9568585 0.76 AURKB (0.58) ALDH1A1HSD17B10AURKAAURKBTTR
SCHEMBL9568549 0.76 AURKB (0.58) ALDH1A1SMN1; SMN2HSD17B10AURKAAURKB
SCHEMBL9568598 0.76 AURKB (0.58) ALDH1A1SMN1; SMN2HSD17B10AURKAAURKB
SCHEMBL9813360 0.76 AURKA (0.72) ALDH1A1HPGDHSD17B10AURKAAURKB
SCHEMBL5711912 0.76 AURKA (0.77) ALDH1A1KDM4ELMNAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4415650-A VACUUM DEPOSITING AN ORGANIC AND AN INORGANIC COMPOUND ON A SUPPORT; THERMOSENSITIVITY; LASERS FUJI PHOTO FILM CO., LTD. (JP) 1983-11-15 US claimed
JP-5222028-A None JP disclosed
EP-1142707-B2 Heat-sensitive lithographic printing plate precursor FUJIFILM CORP (JP) 2011-11-30 EP disclosed
EP-1586461-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2008-03-05 EP disclosed
EP-1593522-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2008-02-27 EP disclosed
EP-1516748-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
US-20070248911-A1 Pattern forming method and bilayer film IWASAWA HARUO 2007-10-25 US disclosed
US-7244549-B2 Pattern forming method and bilayer film JSR CORPORATION (JP) 2007-07-17 US disclosed
EP-1518712-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2007-01-10 EP disclosed
EP-1464514-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-12-27 EP disclosed
EP-1247644-A2 Support for lithographic printing plate and original forme for lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-10-09 EP disclosed
US-20020033108-A1 Heat-sensitive lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-03-21 US disclosed
EP-1142707-A1 Heat-sensitive lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-10-10 EP disclosed
JP-H05222028-A PRODUCTION OF 4-SULFONAPHTHALIC ACID ANHYDRIDE NIPPON STEEL CHEM CO LTD 1993-08-31 JP disclosed
US-4415650-A VACUUM DEPOSITING AN ORGANIC AND AN INORGANIC COMPOUND ON A SUPPORT; THERMOSENSITIVITY; LASERS FUJI PHOTO FILM CO., LTD. (JP) 1983-11-15 US disclosed
US-4317682-A A SULFONAMIDE AND AMINE-CONTAINING AROMATIC POLYCYCLIC COMPOUND AS FLOW CONTROL AGENTS IN PRINTING INKS AND PAINTS; STORAGE STABILITY TOYO INK MANUFACTURING CO. LTD. (JP) 1982-03-02 US disclosed
US-4212813-A OXIDIZING ACENAPHTHENES, COBALT COMPOUND CATALYST NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1980-07-15 US disclosed
US-4171459-A Manufacture of α-naphthol BASF AKTIENGESELLSCHAFT (DE) 1979-10-16 US disclosed
US-4143050-A MANUFACTURE OF 3-HALOSULFONYLTHIOPHENE-CARBOXYLIC ACID COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4117019-A MANUFACTURE OF O-BENZYLTOLUENES BASF AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed