Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956523 | 0.96 | ALDH1A1 (0.62) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL210600 | 0.92 | KDM4E (0.62) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL29417693 | 0.92 | KDM4E (0.62) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL3427377 | 0.87 | HRH3 (0.54) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL17296202 | 0.85 | HRH3 (0.62) | ALDH1A1KDM4ETSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL1039170 | 0.84 | KDM4E (0.64) | ALDH1A1KDM4ETSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2425484 | 0.83 | KDM4E (0.63) | ALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7956588 | 0.83 | DRD3 (0.59) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2427264 | 0.82 | DRD3 (0.58) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 | |
| SCHEMBL30724528 | 0.81 | MAOA (0.64) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184222-A1 | INHIBITORS OF HEPATOCYTE GROWTH FACTOR [HGF] AND MACROPHAGE STIMULATING PROTEIN [MSP] MATURATION | SOUTHERN RESEARCH INSTITUTE (US) | 2015-12-03 | — | — | WO | disclosed |