Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | SCN1A | P35498 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730254 | 0.96 | HRH3 (0.68) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| SCHEMBL210577 | 0.91 | LTA4H (0.63) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| Hydrochloric Acid SCHEMBL5692401 | 0.90 | NPC1 (0.63) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| SCHEMBL30409990 | 0.87 | HRH3 (0.65) | HRH3ALDH1A1KCNH2LMNAKDM4E | |
| SCHEMBL30411052 | 0.85 | HRH3 (0.68) | HRH3KCNH2LMNAMEN1KMT2A | |
| SCHEMBL30409967 | 0.85 | MEN1 (0.66) | HRH3KCNH2LMNAMEN1KMT2A | |
| SCHEMBL30410512 | 0.85 | MEN1 (0.66) | HRH3KCNH2LMNAMEN1KMT2A | |
| SCHEMBL17296296 | 0.85 | ALDH1A1 (0.68) | ALDH1A1SIGMAR1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL30409879 | 0.84 | HRH3 (0.67) | HRH3KCNH2LMNAMEN1KMT2A | |
| SCHEMBL30410433 | 0.84 | HRH3 (0.67) | HRH3KCNH2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168396-B1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIV FRANCHE COMTE (FR) | 2024-07-31 | — | — | EP | disclosed |
| EP-4168396-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Universite De Franche Comte (FR) | 2023-04-26 | — | — | EP | disclosed |
| WO-2021260072-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIVERSITE DE FRANCHE COMTE (FR) | 2021-12-30 | — | — | WO | disclosed |
| EP-3929186-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Université de Franche-Comté (FR) | 2021-12-29 | — | — | EP | disclosed |
| WO-2015184222-A1 | INHIBITORS OF HEPATOCYTE GROWTH FACTOR [HGF] AND MACROPHAGE STIMULATING PROTEIN [MSP] MATURATION | SOUTHERN RESEARCH INSTITUTE (US) | 2015-12-03 | — | — | WO | disclosed |