Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 2/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 3/20 | 0.44 |
| ▸ | SKP1 | P63208 | 3/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727946 | 0.88 | HRH4 (0.51) | HRH4CRHBPCRHR2SMN1; SMN2F10 | |
| SCHEMBL3269967 | 0.84 | F10 (0.49) | HRH4CRHBPCRHR2SMN1; SMN2F10 | |
| SCHEMBL3256156 | 0.80 | KDM4E (0.62) | HRH4CRHBPCRHR2SMN1; SMN2MAPT | |
| SCHEMBL20507928 | 0.80 | HRH3 (0.57) | HRH4HRH3CKS1BSKP1SKP2 | |
| SCHEMBL1775505 | 0.80 | LMNA (0.55) | HRH4SMN1; SMN2F10MAPTKDM4E | |
| SCHEMBL6023878 | 0.80 | LMNA (0.55) | HRH4SMN1; SMN2F10MAPTKDM4E | |
| SCHEMBL5076737 | 0.80 | LMNA (0.55) | HRH4SMN1; SMN2F10MAPTKDM4E | |
| SCHEMBL1727659 | 0.77 | CRHBP (0.46) | HRH4CRHBPCRHR2SMN1; SMN2F10 | |
| SCHEMBL1727683 | 0.77 | MAPT (0.52) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1728825 | 0.76 | CKS1B (0.47) | SMN1; SMN2KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |