Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CKS1B | P61024 | 4/20 | 0.48 |
| ▸ | SKP1 | P63208 | 4/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | KDM6B | O15054 | 2/20 | 0.48 |
| ▸ | KDM6A | O15550 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266146 | 0.86 | TDP1 (0.46) | MAPTHPGDUSP2SMN1; SMN2POLB | |
| SCHEMBL1729229 | 0.80 | TDP1 (0.49) | MAPTHPGDUSP2SMN1; SMN2POLB | |
| SCHEMBL22776419 | 0.80 | ALDH1A1 (0.52) | HPGDALDH1A1CKS1BSKP1SKP2 | |
| SCHEMBL1729630 | 0.77 | HRH4 (0.53) | MAPTHPGDSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1728686 | 0.74 | CKS1B (0.54) | HPGDALDH1A1TSHRCKS1BSKP1 | |
| SCHEMBL3648472 | 0.73 | DKK1 (0.57) | CKS1BSKP1SKP2MAOB | |
| SCHEMBL1729041 | 0.72 | NPC1 (0.55) | SMN1; SMN2TSHRCKS1BSKP1SKP2 | |
| SCHEMBL1728825 | 0.71 | CKS1B (0.47) | HPGDSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL20507928 | 0.70 | HRH3 (0.57) | CKS1BSKP1SKP2 | |
| SCHEMBL3650734 | 0.70 | F10 (0.51) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |