Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19490691 | 0.86 | MAPT (0.47) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL19624623 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL16620935 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL16620938 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL5178571 | 0.78 | GRIN2D (0.53) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL31682616 | 0.78 | GRIN2D (0.53) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL9754405 | 0.78 | GRIN2D (0.53) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL3365481 | 0.78 | ALDH1A1 (0.60) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL802774 | 0.78 | ALDH1A1 (0.60) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| Lithium Ion SCHEMBL3399785 | 0.77 | ALDH1A1 (0.59) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199972-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-01 | — | — | US | disclosed |