Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178571 | 1.00 | GRIN2D (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31682616 | 1.00 | GRIN2D (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3082834 | 0.93 | MAOB (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL23265029 | 0.87 | MAPT (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL20871094 | 0.87 | MAOB (0.56) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5179901 | 0.87 | NFE2L2 (0.65) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL16322264 | 0.85 | ALDH1A1 (0.55) | MAOBKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16322265 | 0.85 | ALDH1A1 (0.55) | MAOBKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14337416 | 0.84 | MAOB (0.71) | MAOBKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL19624623 | 0.82 | SMN1; SMN2 (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282713-A1 | EFFICIENT CAPTURE AND RELEASE OF THE RARE-EARTH ELEMENTS USING COVALENT ORGANIC FRAMEWORKS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2025-09-11 | — | — | US | disclosed |
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | THE UNIVERSITY OF CHICAGO (US) | 2021-03-23 | — | — | US | disclosed |
| CN-106748952-B | β -ester base-butyrolactam and γ -ester base-δ-valerolactam synthetic method | 大连大学 | 2019-05-07 | — | — | CN | disclosed |
| US-20180361370-A1 | STABILIZATION OF ACTIVE METAL CATALYSTS AT METAL-ORGANIC FRAMEWORK NODES FOR HIGHLY EFFICIENT ORGANIC TRANSFORMATIONS | NATIONAL SCIENCE FOUNDATION | 2018-12-20 | — | — | US | disclosed |
| CN-106748952-A | The synthetic method of β ester group γ butyrolactams and γ ester group δ valerolactams | 大连大学 | 2017-05-31 | — | — | CN | disclosed |
| WO-1991013065-A1 | 6-ARYL-2-SUBSTITUTED BENZOIC ACID HERBICIDES | FMC CORPORATION (US) | 1991-09-05 | — | — | WO | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250282713-A1 | EFFICIENT CAPTURE AND RELEASE OF THE RARE-EARTH ELEMENTS USING COVALENT ORGANIC FRAMEWORKS | NXF1, YBX1, SRSF1 | GRIN2D 3044/4885GRIN3B 2691/4885GRIN1 1310/4885 |
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | SBK1, SIK1, SIK2 | GRIN2D 2001/4885GRIN3B 3456/4885GRIN1 1936/4885 |
| US-20180361370-A1 | STABILIZATION OF ACTIVE METAL CATALYSTS AT METAL-ORGANIC FRAMEWORK NODES FOR HIGHLY EFFICIENT ORGANIC TRANSFORMATIONS | SBK1, SIK1, SIK2 | GRIN2D 2001/4885GRIN3B 3456/4885GRIN1 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.