Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL802774 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| Lithium Ion SCHEMBL3399785 | 0.98 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| SCHEMBL22624708 | 0.85 | SIRT2 (0.57) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| SCHEMBL2492349 | 0.84 | SIRT2 (0.74) | ALDH1A1MAPTKDM4EHTTSIRT2 | |
| SCHEMBL2937662 | 0.84 | SIRT2 (0.74) | ALDH1A1MAPTKDM4EHTTSIRT2 | |
| SCHEMBL2492350 | 0.84 | SIRT2 (0.74) | ALDH1A1MAPTKDM4EHTTSIRT2 | |
| SCHEMBL3365845 | 0.83 | SIRT2 (0.73) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| SCHEMBL3365850 | 0.83 | SIRT2 (0.73) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| SCHEMBL22624795 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| SCHEMBL16620935 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9437828-B2 | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| US-20150065725-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| US-8883325-B2 | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20120205638-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | US | disclosed |
| CN-101601329-B | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH | 2012-07-11 | — | — | CN | disclosed |
| US-20100327264-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATNET GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| EP-2095690-B1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2010-10-13 | — | — | EP | disclosed |
| CN-101601329-A | Adopt the electroluminescent device of azomethine-lithium-complex as electron injecting layer | MERCK PATENT GMBH (DE) | 2009-12-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120205638-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | ACSL3, APOL1, INTS9 | ALDH1A1 2269/4885MAPT 3539/4885HPGD 3789/4885 |
| US-20100327264-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | ACSL3, APOL1, INTS9 | ALDH1A1 2201/4885MAPT 3581/4885HPGD 3799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.