SCHEMBL17298741

SCHEMBL17298741

CCOC(=O)c1cc(COc2ccc(C)cc2)on1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 13/20 0.55
NPC1 O15118 10/20 0.55
ADRB2 P07550 1/20 0.55
MAPT P10636 4/20 0.52
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.47
HSP90AA1 P07900 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAOB P27338 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17288680 0.90 ALDH1A1 (0.52) RAB9ANPC1MAPTALDH1A1L3MBTL1
SCHEMBL15931944 0.90 MAPT (0.50) RAB9ANPC1ADRB2MAPTALDH1A1
SCHEMBL15931831 0.90 MAPT (0.64) RAB9ANPC1MAPTALDH1A1L3MBTL1
SCHEMBL15932182 0.89 MAPT (0.63) RAB9ANPC1MAPTALDH1A1L3MBTL1
SCHEMBL15931959 0.87 ADRB2 (0.58) RAB9ANPC1ADRB2MAPTALDH1A1
SCHEMBL17298747 0.87 RAB9A (0.63) RAB9ANPC1KMT2A
SCHEMBL15931997 0.86 KMT2A (0.56) RAB9ANPC1ADRB2MAPTALDH1A1
SCHEMBL17298745 0.86 RAB9A (0.54) RAB9ANPC1MAPTLMNAL3MBTL1
SCHEMBL15931958 0.85 MAPT (0.53) RAB9ANPC1MAPTALDH1A1LMNA
SCHEMBL17298742 0.85 RAB9A (0.58) RAB9ANPC1ADRB2MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 RAB9A 400/4885NPC1 3630/4885ADRB2 1204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.