SCHEMBL17300201

SCHEMBL17300201

c1ccc2c(c1)nc(-c1ccc(-c3ccc4c5ccccc5c5ccccc5c4c3)cc1)c1c3ccccc3c3ccccc3c21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 4/20 0.42
KDM4E B2RXH2 4/20 0.40
LMNA P02545 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
GAA P10253 1/20 0.40
ADORA2A P29274 3/20 0.39
NUDT1 P36639 1/20 0.39
DHFR P00374 1/20 0.38
PDE10A Q9Y233 3/20 0.38
PIK3CD O00329 1/20 0.38
PIK3CA P42336 1/20 0.38
PIK3CB P42338 1/20 0.38
MTOR P42345 1/20 0.38
PIK3CG P48736 1/20 0.38
ALDH1A1 P00352 2/20 0.37
ATM Q13315 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17300203 0.93 MEN1 (0.49) DHODHKDM4ELMNAMEN1KMT2A
SCHEMBL17914756 0.91 DHODH (0.47) DHODHKDM4ELMNAMEN1KMT2A
SCHEMBL17914887 0.90 ADORA2A (0.39) DHODHKDM4ELMNAMEN1KMT2A
SCHEMBL17914707 0.90 DHODH (0.50) DHODHKDM4ELMNAMEN1KMT2A
SCHEMBL17914812 0.89 DHODH (0.44) DHODHKDM4ELMNAMEN1KMT2A
SCHEMBL17914714 0.88 DHODH (0.46) DHODHKDM4ELMNAMEN1KMT2A
SCHEMBL17300215 0.88 DHODH (0.48) DHODHLMNAMEN1KMT2APIK3CA
SCHEMBL17300237 0.88 DHODH (0.40) DHODHKDM4ELMNAMEN1KMT2A
SCHEMBL17914710 0.87 ESR1 (0.43) DHODHKDM4ELMNAL3MBTL1TDP1
SCHEMBL17914759 0.87 DHODH (0.42) DHODHKDM4ELMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10608189-B2 Condensed cyclic compounds and organic light-emitting devices including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-03-31 US disclosed
US-20160204357-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME HEESUNG MATERIAL LTD. (KR) 2016-07-14 US disclosed
US-20160204357-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME HEESUNG MATERIAL LTD. (KR) 2016-07-14 US disclosed
US-20150349275-A1 CONDENSED CYCLIC COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-03 US disclosed
US-20150349275-A1 CONDENSED CYCLIC COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10608189-B2 Condensed cyclic compounds and organic light-emitting devices including the same CRY1, CRY2, CCNE2 DHODH 1979/4885KDM4E 3625/4885LMNA 1284/4885
US-20160204357-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME NOTUM, ORC3, PPOX DHODH 129/4885KDM4E 2672/4885LMNA 2886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.