Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 2/20 | 0.35 |
| ▸ | SKP1 | P63208 | 2/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729260 | 0.89 | HTR3A (0.42) | CHRM4CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL1728923 | 0.88 | HRH3 (0.49) | CHRM4ACHEHRH3MCHR1ENPP1 | |
| SCHEMBL1729777 | 0.88 | SMO (0.40) | CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL1729234 | 0.83 | ENPP1 (0.42) | ACHEENPP1 | |
| SCHEMBL1728885 | 0.80 | CHRM4 (0.53) | CHRM4ACHEABL1ENPP1 | |
| SCHEMBL3270570 | 0.79 | CHRM4 (0.46) | CHRM4ACHEABL1ENPP1 | |
| SCHEMBL1727774 | 0.79 | HRH3 (0.48) | CHRM4ACHEHRH3MCHR1 | |
| SCHEMBL1728139 | 0.79 | CHRM4 (0.39) | CHRM4ABL1MAP4K4 | |
| SCHEMBL1729776 | 0.79 | HRH3 (0.47) | CHRM4ACHEHRH3HSD17B10CKS1B | |
| SCHEMBL1730249 | 0.77 | HTR3A (0.42) | CHRM4CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |