Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 9/20 | 0.39 |
| ▸ | SKP1 | P63208 | 9/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 9/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729260 | 0.87 | HTR3A (0.42) | HTR3ACKS1BSKP1SKP2CHRM4 | |
| SCHEMBL1729037 | 0.84 | HCAR2 (0.46) | HTR3ACKS1BSKP1SKP2SMN1; SMN2 | |
| SCHEMBL1727953 | 0.83 | PDE10A (0.45) | HTR3ASMN1; SMN2 | |
| SCHEMBL1729269 | 0.83 | AKR1C3 (0.45) | HTR3ACHRM4 | |
| SCHEMBL1728042 | 0.83 | RXRA (0.46) | AOC3CKS1BSKP1SKP2CHRM4 | |
| SCHEMBL1730190 | 0.81 | CHRM4 (0.44) | AOC3KDM1ATNFLMNASTAT3 | |
| SCHEMBL1730164 | 0.81 | DEGS1 (0.47) | AOC3KDM1ATNFLMNASTAT3 | |
| SCHEMBL1727572 | 0.80 | CNR1 (0.41) | AOC3CKS1BSKP1SKP2 | |
| SCHEMBL1729384 | 0.80 | DPP4 (0.44) | — | |
| SCHEMBL1727978 | 0.80 | KDM1A (0.43) | AOC3KDM1ALMNASMN1; SMN2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |