Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.60 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.58 |
| ▸ | DUSP22 | Q9NRW4 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL20582561 | 0.90 | THRB (0.76) | THRBMEN1KMT2ADUSP3POLB | |
| SCHEMBL11332371 | 0.87 | THRB (0.72) | THRBMEN1KMT2ADUSP3POLB | |
| SCHEMBL9911664 | 0.87 | MEN1 (0.62) | THRBMEN1KMT2ADUSP3POLB | |
| SCHEMBL10035996 | 0.81 | DUSP22 (0.77) | THRBMEN1KMT2ADUSP3POLB | |
| SCHEMBL12123516 | 0.81 | DUSP22 (0.77) | THRBMEN1KMT2ADUSP3POLB | |
| SCHEMBL9917038 | 0.81 | DUSP22 (0.77) | THRBMEN1KMT2ADUSP3POLB | |
| SCHEMBL12013725 | 0.79 | MEN1 (0.68) | THRBMEN1KMT2ADUSP3POLB | |
| SCHEMBL17295556 | 0.77 | S1PR3 (0.73) | THRBMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL17295555 | 0.77 | S1PR3 (0.73) | THRBMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL13381732 | 0.77 | HPGD (0.56) | THRBMEN1KMT2ADUSP3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181337-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2015-12-03 | — | — | WO | disclosed |