Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17368070 | 0.84 | L3MBTL1 (0.47) | L3MBTL1ZDHHC7GPR84ABCB1FFAR4 | |
| SCHEMBL17368067 | 0.84 | L3MBTL1 (0.47) | L3MBTL1ZDHHC7GPR84ABCB1FFAR4 | |
| SCHEMBL17368080 | 0.84 | L3MBTL1 (0.47) | L3MBTL1ZDHHC7GPR84ABCB1FFAR4 | |
| SCHEMBL10487617 | 0.82 | ZDHHC7 (0.61) | ZDHHC7GPR84ABCB1FFAR1CA1 | |
| SCHEMBL11725954 | 0.82 | ZDHHC7 (0.61) | ZDHHC7GPR84ABCB1FFAR1CA1 | |
| SCHEMBL668999 | 0.82 | ZDHHC7 (0.61) | ZDHHC7GPR84ABCB1FFAR1CA1 | |
| SCHEMBL17199810 | 0.81 | GPR84 (0.47) | L3MBTL1GPR84FFAR4FFAR1LMNA | |
| SCHEMBL6172244 | 0.81 | ZDHHC7 (0.58) | ZDHHC7GPR84ABCB1FFAR1CA1 | |
| SCHEMBL17302556 | 0.78 | GPR84 (0.45) | L3MBTL1GPR84FFAR4FFAR1FAAH | |
| SCHEMBL26039947 | 0.77 | GPR84 (0.47) | L3MBTL1GPR84FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015184256-A2 | BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2015-12-03 | — | — | WO | disclosed |