Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729052 | 0.92 | NPC1 (0.43) | CNR1ITGB3ITGA2BAOC3HTR1A | |
| SCHEMBL1727919 | 0.84 | GRIN2D (0.37) | AOC3TDP1DRD2DRD3CHRM2 | |
| SCHEMBL1727912 | 0.83 | CNR1 (0.42) | CNR1PKMPIM2AOC3PIM1 | |
| SCHEMBL1727572 | 0.81 | CNR1 (0.41) | CNR1PKMPIM2AOC3PIM1 | |
| SCHEMBL27629097 | 0.80 | CNR1 (0.47) | CNR1PIM2PIM1TDP1FFAR4 | |
| SCHEMBL1728878 | 0.80 | AOC3 (0.46) | AOC3HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL1710989 | 0.77 | CNR1 (0.47) | CNR1PIM2PIM1FFAR4 | |
| SCHEMBL1729255 | 0.75 | HTR1A (0.43) | CNR1AOC3HTR1ADRD2DRD4 | |
| SCHEMBL1729927 | 0.75 | KDM4E (0.42) | PIM1HTR1ADRD2HTR7 | |
| SCHEMBL14797064 | 0.75 | ITGB3 (0.40) | CNR1PKMITGB3ITGA2BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |