Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730021 | 0.92 | HTR1A (0.41) | KDM4ERECQLKMT2AHTR1ADRD2 | |
| SCHEMBL1727621 | 0.84 | KMT2A (0.42) | KDM4ERECQLKMT2AMALT1ALDH1A1 | |
| SCHEMBL1727885 | 0.83 | KDM4E (0.41) | KDM4ERECQLKMT2AHTR1ADRD2 | |
| SCHEMBL1729231 | 0.81 | KDM4E (0.40) | KDM4ERECQLKMT2AHTR1ADRD2 | |
| SCHEMBL1728878 | 0.77 | AOC3 (0.46) | KDM4EHTR1AAURKAKDRAURKB | |
| SCHEMBL1730244 | 0.76 | FFAR4 (0.40) | KDM4ERECQLKMT2AHTR1ADRD2 | |
| SCHEMBL1730282 | 0.75 | CNR1 (0.43) | HTR1ADRD2HTR7PIM1 | |
| SCHEMBL1728840 | 0.74 | HTR1A (0.39) | KDM4ERECQLKMT2AHTR1ADRD2 | |
| SCHEMBL3269143 | 0.74 | CKS1B (0.42) | KDM4ERECQLKMT2AHTR1ADRD2 | |
| SCHEMBL1727561 | 0.73 | KMT2A (0.48) | KDM4ERECQLKMT2AMALT1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |