Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19076086 | 0.92 | LNPEP (0.53) | LNPEP | |
| SCHEMBL17303639 | 0.84 | LNPEP (0.50) | LNPEP | |
| SCHEMBL9129897 | 0.84 | CYP2C9 (0.45) | LNPEP | |
| SCHEMBL9669619 | 0.77 | KMT2A (0.42) | LNPEP | |
| SCHEMBL29380253 | 0.77 | KMT2A (0.42) | LNPEP | |
| SCHEMBL23554280 | 0.76 | NOS2 (0.44) | LNPEP | |
| SCHEMBL29550059 | 0.76 | NOS2 (0.44) | LNPEP | |
| SCHEMBL2454070 | 0.76 | CYP2D6 (0.46) | LNPEP | |
| SCHEMBL6376429 | 0.75 | MAOB (0.47) | LNPEP | |
| SCHEMBL13097218 | 0.75 | LNPEP (0.43) | LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975091-B2 | Pyridine derivative | ASTELLAS PHARMA INC. (JP) | 2021-04-13 | — | — | US | disclosed |
| US-10975091-B2 | Pyridine derivative | ASTELLAS PHARMA INC. (JP) | 2021-04-13 | — | — | US | disclosed |
| EP-3150581-B1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2020-04-15 | — | — | EP | disclosed |
| EP-3150581-B1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2020-04-15 | — | — | EP | disclosed |
| US-20200055868-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-20200055868-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-10421762-B2 | Pyridine derivative | ASTELLAS PHARMA INC. (JP) | 2019-09-24 | — | — | US | disclosed |
| US-10421762-B2 | Pyridine derivative | ASTELLAS PHARMA INC. (JP) | 2019-09-24 | — | — | US | disclosed |
| US-20180327418-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2018-11-15 | — | — | US | disclosed |
| US-10059720-B2 | Pyridine derivative | ASTELLAS PHARMA INC. (JP) | 2018-08-28 | — | — | US | disclosed |
| US-20170190715-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2017-07-06 | — | — | US | disclosed |
| US-20170190715-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2017-07-06 | — | — | US | disclosed |
| US-20170190715-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2017-07-06 | — | — | US | disclosed |
| EP-3150581-A1 | PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2017-04-05 | — | — | EP | disclosed |
| EP-3150581-A1 | PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015182686-A1 | PYRIDINE DERIVATIVE | アステラス製薬株式会社 | 2015-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055868-A1 | PYRIDINE DERIVATIVE | LAP3, PREP, DNPEP | LNPEP 5/4885 |
| US-10975091-B2 | Pyridine derivative | LAP3, PREP, DNPEP | LNPEP 5/4885 |
| US-20180327418-A1 | PYRIDINE DERIVATIVE | LAP3, PREP, DNPEP | LNPEP 5/4885 |
| US-10059720-B2 | Pyridine derivative | LAP3, PREP, DNPEP | LNPEP 5/4885 |
| US-10421762-B2 | Pyridine derivative | LAP3, PREP, DNPEP | LNPEP 5/4885 |
| US-20170190715-A1 | PYRIDINE DERIVATIVE | LAP3, PREP, DNPEP | LNPEP 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.