Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173043 | 0.88 | ESR1 (0.50) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL13473211 | 0.83 | ESR1 (0.45) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL13917741 | 0.83 | ESR1 (0.45) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL95390 | 0.82 | POLB (0.47) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL24952432 | 0.80 | ESR1 (0.42) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL13451844 | 0.79 | ESR1 (0.41) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL94806 | 0.77 | KDM4E (0.42) | ESR1CYP3A4HPGDHSD17B10ALDH1A1 | |
| SCHEMBL19318213 | 0.77 | APP (0.38) | HPGDHSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL13376147 | 0.77 | KDM4E (0.42) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL13979486 | 0.76 | TSHR (0.47) | ESR1ESR2CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245263-A1 | FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN COMPOSITION | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2012-09-27 | — | — | US | disclosed |
| US-20120059098-A1 | FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN COMPOSITION | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |
| US-20120059099-A1 | FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN COMPOSITION | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |