Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | WDR5 | P61964 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593520 | 0.92 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30356865 | 0.92 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL20421660 | 0.84 | WDR5 (0.49) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18803862 | 0.83 | MAPT (0.67) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14134529 | 0.83 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16384835 | 0.83 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3196806 | 0.82 | WDR5 (0.58) | MEN1KMT2AALDH1A1KDM4EWDR5 | |
| SCHEMBL14225351 | 0.82 | WDR5 (0.79) | ALDH1A1KDM4EHPGDWDR5NR4A2 | |
| SCHEMBL22650975 | 0.81 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL246068 | 0.80 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046915-B1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |