Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356865 | 0.88 | MAPT (0.61) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL593520 | 0.88 | MAPT (0.61) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12486711 | 0.85 | MAPT (0.54) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7988831 | 0.83 | MEN1 (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14134529 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16384835 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17304516 | 0.81 | MAPT (0.55) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18803862 | 0.80 | MAPT (0.67) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7985137 | 0.80 | WDR5 (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL246068 | 0.79 | MAPT (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319266-B2 | Syntheses, characterizations, and applications of heli-acenes | University of Wyoming-Office of Research & Economic Development (US) | 2022-05-03 | — | — | US | disclosed |
| US-20200354294-A1 | SYNTHESES, CHARACTERIZATIONS, AND APPLICATIONS OF HELI-ACENES | UNIVERSITY OF WYOMING (US) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319266-B2 | Syntheses, characterizations, and applications of heli-acenes | HRH1, EHD1, CRY1 | MAPT 1643/4885MEN1 3272/4885KMT2A 3604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.