SCHEMBL17305657

SCHEMBL17305657

c1ccc(-c2ccc(-c3nc(-n4c5ccccc5c5c6sc7ccccc7c6c6ccccc6c54)nc4c3oc3ccccc34)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.33
TSHR P16473 4/20 0.33
LMNA P02545 4/20 0.32
KMT2A Q03164 3/20 0.32
POLB P06746 2/20 0.32
HTT P42858 1/20 0.32
KDM4E B2RXH2 3/20 0.32
HSD17B10 Q99714 2/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 5/20 0.32
HPGD P15428 1/20 0.32
MEN1 O00255 2/20 0.31
PTGER1 P34995 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ADORA2A P29274 1/20 0.31
CSF1R P07333 1/20 0.31
PDGFRB P09619 1/20 0.31
KIT P10721 1/20 0.31
FLT3 P36888 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17305654 0.98 MAPT (0.34) MAPTTSHRLMNAKMT2APOLB
SCHEMBL17297616 0.95 MAPT (0.32) MAPTTSHRLMNAKMT2APOLB
SCHEMBL17305662 0.94 TSHR (0.31) MAPTTSHRLMNAKMT2APOLB
SCHEMBL17305659 0.94 MAPT (0.32) MAPTTSHRLMNAKMT2APOLB
SCHEMBL17297403 0.94 MAPT (0.34) MAPTTSHRLMNAKMT2APOLB
SCHEMBL17305772 0.94 MAPT (0.34) MAPTTSHRLMNAKMT2APOLB
SCHEMBL17297407 0.93 MAPT (0.33) MAPTTSHRLMNAKMT2APOLB
SCHEMBL17305661 0.92 NPC1 (0.33)
SCHEMBL17305771 0.92 MAPT (0.35) MAPTTSHRLMNAKMT2APOLB
SCHEMBL17297455 0.92 MAPT (0.35) MAPTTSHRLMNAKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9570689-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2017-02-14 US disclosed
US-9570689-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2017-02-14 US disclosed
EP-2949725-B1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO LTD (KR) 2016-12-14 EP disclosed
US-20160233433-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-08-11 US disclosed
US-20160233433-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-08-11 US disclosed
US-9331288-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof SAMSUNG DISPLAY CO., LTD. (KR) 2016-05-03 US disclosed
US-9331288-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof SAMSUNG DISPLAY CO., LTD. (KR) 2016-05-03 US disclosed
US-20150349272-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150349272-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, ORAI2 MAPT 2247/4885TSHR 4752/4885LMNA 1420/4885
US-20160233433-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, LEF1, TMEM109 MAPT 3397/4885TSHR 4639/4885LMNA 1066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.