Sugi Predict

Sugi Predict / Compounds / SCHEMBL10138306

SCHEMBL10138306

SCHEMBL10138306

CNC(=O)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.69
▸ L3MBTL1 Q9Y468 1/20 0.69
▸ CA9 Q16790 11/20 0.64
▸ MEN1 O00255 2/20 0.58
▸ POLB P06746 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ ALPL P05186 1/20 0.58
▸ ALPI P09923 1/20 0.58
▸ ALPG P10696 1/20 0.58
▸ DNASE1L3 Q13609 1/20 0.57
▸ PRMT1 Q99873 1/20 0.57
▸ CA1 P00915 9/20 0.56
▸ CA2 P00918 9/20 0.56
▸ ATM Q13315 1/20 0.56
▸ PLEC Q15149 1/20 0.56
▸ CA12 O43570 3/20 0.54
▸ ESR1 P03372 1/20 0.54
▸ ALB P02768 1/20 0.54
▸ SLC5A2 P31639 1/20 0.52
▸ CA14 Q9ULX7 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13785142 0.93 DNASE1L3 (0.63) USP2L3MBTL1CA9MEN1POLB
SCHEMBL13656547 0.90 USP2 (0.72) USP2L3MBTL1CA9MEN1POLB
SCHEMBL1437042 0.89 USP2 (0.78) USP2L3MBTL1CA9MEN1POLB
SCHEMBL10153957 0.89 USP2 (0.66) USP2L3MBTL1CA9MEN1POLB
SCHEMBL20053383 0.89 USP2 (0.66) USP2L3MBTL1CA9MEN1POLB
SCHEMBL10123977 0.89 USP2 (0.66) USP2L3MBTL1CA9MEN1POLB
SCHEMBL173061 0.89 USP2 (0.73) USP2L3MBTL1CA9MEN1POLB
SCHEMBL23258882 0.88 USP2 (0.63) USP2L3MBTL1CA9MEN1POLB
SCHEMBL92536 0.87 USP2 (0.62) USP2L3MBTL1CA9MEN1POLB
SCHEMBL19423916 0.86 USP2 (0.73) USP2L3MBTL1CA9MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3000833-B1 MICELLES COMPRISING A TRIBLOCK COPOLYMER AND A THERAPEUTIC AGENT INTEZYNE TECH INC (US) 2019-09-04 — — EP disclosed
US-20170253699-A1 BLOCK COPOLYMERS FOR STABLE MICELLES INTEZYNE TECHNOLOGIES, INC. 2017-09-07 — — US disclosed
US-20170240703-A1 BLOCK COPOLYMERS FOR STABLE MICELLES INTEZYNE TECHNOLOGIES, INC. 2017-08-24 — — US disclosed
US-9499665-B2 Block copolymers for stable micelles INTEZYNE TECHNOLOGIES, INC. (US) 2016-11-22 — — US disclosed
US-20160264732-A1 BLOCK COPOLYMERS FOR STABLE MICELLES INTEZYNE TECHNOLOGIES, INC. 2016-09-15 — — US disclosed
EP-3000833-A1 BLOCK COPOLYMERS FOR STABLE MICELLES Intezyne Technologies Inc. (US) 2016-03-30 — — EP disclosed
US-20150368401-A1 BLOCK COPOLYMERS FOR STABLE MICELLES INTEZYNE TECHNOLOGIES, INC. 2015-12-24 — — US disclosed
EP-2660255-B1 Block copolymers for stable micelles INTEZYNE TECHNOLOGIES INC (US) 2015-10-28 — — EP disclosed
US-20150232616-A1 HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS INTEZYNE TECHNOLOGIES, INC. 2015-08-20 — — US disclosed
US-9078930-B2 Block copolymers for stable micelles INTEZYNE TECHNOLOGIES, INC. (US) 2015-07-14 — — US disclosed
US-20120046757-A1 COVALENT MODIFICATION OF METAL SURFACES INTEZYNE TECHNOLOGIES (US) 2012-02-23 — — US disclosed
US-20120046735-A1 PLASMA MODIFICATION OF METAL SURFACES INTEZYNE TECHNOLOGIES, INCORPORATED (US) 2012-02-23 — — US disclosed
US-20120046757-A1 COVALENT MODIFICATION OF METAL SURFACES INTEZYNE TECHNOLOGIES (US) 2012-02-23 — — US disclosed
US-8066824-B2 Covalent modification of metal surfaces INTEZYNE TECHNOLOGIES, INC. (US) 2011-11-29 — — US disclosed
US-20100331542-A1 PROBES FOR ANIONIC CELL SURFACE DETECTION UNIVERSITY OF NOTRE DAME DU LAC (US) 2010-12-30 — — US disclosed
US-20090173631-A1 Single Cell Analysis of Membrane Molecules ACLARA BIOSCIENCES, INC. 2009-07-09 — — US disclosed
US-20090011432-A1 Detecting and Profiling Molecular Complexes MONOGRAM BIOSCIENCES, INC. (US) 2009-01-08 — — US disclosed
US-7402397-B2 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. (US) 2008-07-22 — — US disclosed
US-20080171351-A1 PROBES FOR ANIONIC CELL SURFACE DETECTION UNIVERSITY OF NOTRE DAME DU LAC (US) 2008-07-17 — — US disclosed
US-20080035243-A1 Covalent modification of metal surfaces INTEZYNE TECHNOLOGIES (US) 2008-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080035243-A1 Covalent modification of metal surfaces ITGAL, ITGA1, ITGA5 USP2 1889/4885L3MBTL1 2292/4885CA9 1058/4885
US-20120046757-A1 COVALENT MODIFICATION OF METAL SURFACES ITGAL, ITGA1, ITGA5 USP2 1889/4885L3MBTL1 2292/4885CA9 1058/4885
US-20100331542-A1 PROBES FOR ANIONIC CELL SURFACE DETECTION ANXA5, ANXA6, ANXA3 USP2 3458/4885L3MBTL1 1739/4885CA9 271/4885
US-20160264732-A1 BLOCK COPOLYMERS FOR STABLE MICELLES ABCB4, CLTB, EPHA2 USP2 735/4885L3MBTL1 2460/4885CA9 2392/4885
US-20170240703-A1 BLOCK COPOLYMERS FOR STABLE MICELLES ABCB4, CLTB, EPHA2 USP2 735/4885L3MBTL1 2460/4885CA9 2392/4885
US-20170253699-A1 BLOCK COPOLYMERS FOR STABLE MICELLES ABCB4, CLTB, EPHA2 USP2 735/4885L3MBTL1 2460/4885CA9 2392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.