Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17307945 | 0.92 | LPAR3 (0.42) | LPAR3LPAR2LPAR1GAAP2RY10 | |
| SCHEMBL26848345 | 0.90 | PLA2G2A (0.38) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL19986467 | 0.90 | LPAR3 (0.40) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL26434943 | 0.81 | LPAR3 (0.38) | LPAR3LPAR2LPAR1 | |
| SCHEMBL1900350 | 0.80 | LPAR3 (0.52) | LPAR3LPAR2LPAR1 | |
| SCHEMBL8860368 | 0.79 | MEN1 (0.55) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL19940133 | 0.79 | LPAR3 (0.34) | LPAR3LPAR2LPAR1P2RY10TSHR | |
| SCHEMBL19940130 | 0.79 | LPAR3 (0.34) | LPAR3LPAR2LPAR1P2RY10TSHR | |
| SCHEMBL19511826 | 0.79 | MEN1 (0.63) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL19511989 | 0.79 | MEN1 (0.63) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078612-A1 | INTRACELLULAR DELIVERY SYSTEM AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-03-22 | — | — | US | disclosed |
| US-20180078612-A1 | INTRACELLULAR DELIVERY SYSTEM AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-03-22 | — | — | US | disclosed |
| US-20150343090-A1 | INTRACELLULAR DELIVERY SYSTEM AND METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-12-03 | — | — | US | disclosed |
| US-20150343090-A1 | INTRACELLULAR DELIVERY SYSTEM AND METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078612-A1 | INTRACELLULAR DELIVERY SYSTEM AND METHODS | LNPEP, CHERP, CHMP4B | MEN1 1866/4885KMT2A 4495/4885THRB 3587/4885 |
| US-20150343090-A1 | INTRACELLULAR DELIVERY SYSTEM AND METHODS | LNPEP, CHERP, CHMP4B | MEN1 1866/4885KMT2A 4495/4885THRB 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.