SCHEMBL1730835

SCHEMBL1730835

Cc1ccc(C(O)CO)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
CYP3A4 P08684 1/20 0.46
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
CHRNA7 P36544 1/20 0.41
ACHE P22303 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
LMNA P02545 1/20 0.39
TAAR1 Q96RJ0 3/20 0.39
HIF1A Q16665 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HTR1A P08908 1/20 0.39
THPO P40225 1/20 0.39
BLM P54132 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NMUR2 Q9GZQ4 1/20 0.39
CYP2C9 P11712 1/20 0.39
HTR3A P46098 1/20 0.38
NFKB1 P19838 1/20 0.38
NR3C2 P08235 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6134241 1.00 TSHR (0.46) TSHRCYP3A4ALDH1A1MAPTCHRNA7
SCHEMBL6493189 1.00 TSHR (0.46) TSHRCYP3A4ALDH1A1MAPTCHRNA7
SCHEMBL28986558 1.00 TSHR (0.46) TSHRCYP3A4ALDH1A1MAPTCHRNA7
SCHEMBL1101003 0.93 ALDH1A1 (0.45) TSHRCYP3A4ALDH1A1MAPTCHRNA7
SCHEMBL17438169 0.87 TSHR (0.48) TSHRCYP3A4ALDH1A1TDP1LMNA
SCHEMBL3176056 0.81 ALDH1A1 (0.42) TSHRALDH1A1MAPTCHRNA7ACHE
SCHEMBL24015469 0.80 TSHR (0.46) TSHRCYP3A4ALDH1A1TDP1LMNA
SCHEMBL874873 0.80 LMNA (0.62) TSHRCYP3A4ALDH1A1MAPTCHRNA7
SCHEMBL3921442 0.80 LMNA (0.62) TSHRCYP3A4ALDH1A1MAPTCHRNA7
SCHEMBL4576404 0.80 LMNA (0.62) TSHRCYP3A4ALDH1A1MAPTCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113842908-A Regulation and control of C-C bond aerobic oxidative cracking product by vanadium oxide-based photocatalyst 天津理工大学 2021-12-28 CN claimed
CN-110713610-A Supermolecule skeleton structure fiber gel, preparation method and application thereof in liquid separation 吉林大学 2020-01-21 CN claimed
CN-105315138-A Synthetic method of p-methylphenyl oxyethyl methyl ether YIN JIANMING 2016-02-10 CN claimed
CN-120040351-A Nitrogen-containing heteroaryl compound, preparation method, intermediate and application thereof 江苏恩华药业股份有限公司 2025-05-27 CN disclosed
CN-119977739-A Method for preparing nitrile compound by oxidizing alcohol compound to break C-C bond 中国科学院大连化学物理研究所 2025-05-13 CN disclosed
CN-113842908-A Regulation and control of C-C bond aerobic oxidative cracking product by vanadium oxide-based photocatalyst 天津理工大学 2021-12-28 CN disclosed
EP-3906969-A1 ANTIHYPERTENSIVE POLYOL COMPOUND AND DERIVATIVE THEREOF East China University of Science and Technology (CN) 2021-11-10 EP disclosed
WO-2020249117-A1 ANTIHYPERTENSIVE POLYOL COMPOUND AND DERIVATIVE THEREOF 华东理工大学 2020-12-17 WO disclosed
CN-110713610-A Supermolecule skeleton structure fiber gel, preparation method and application thereof in liquid separation 吉林大学 2020-01-21 CN disclosed
CN-105315138-A Synthetic method of p-methylphenyl oxyethyl methyl ether YIN JIANMING 2016-02-10 CN disclosed
US-9017449-B2 Nanowire preparation methods, compositions, and articles CARESTREAM HEALTH, INC. (US) 2015-04-28 US disclosed
WO-1997020802-A1 INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE VENANTIUS LIMITED (IE) 1997-06-12 WO disclosed
US-5244879-A 23-nor-23-oxa avermectin analogs are active anthelmintic agents MERCK & CO., INC. (US) 1993-09-14 US disclosed
US-5214169-A N-(2,3-epoxycyclopentyl) carbamate derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1993-05-25 US disclosed
EP-0339564-B1 CARBAMATE DERIVATIVES AND A PROCESS FOR THEIR PRODUCTION MERRELL DOW PHARMACEUTICALS INC. (US) 1993-02-03 EP disclosed
EP-0032062-B2 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
EP-0339564-A1 Carbamate derivatives and a process for their production MERRELL DOW PHARMACEUTICALS INC. (US) 1989-11-02 EP disclosed
EP-0032062-B1 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-04-03 EP disclosed
US-4345054-A High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-17 US disclosed
EP-0032062-A2 High-molecular-weight novolak substituted phenolic resins and their preparation MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-07-15 EP disclosed