Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921442 | 1.00 | LMNA (0.62) | LMNAALDH1A1MAPTSMN1; SMN2PGR | |
| SCHEMBL4576404 | 1.00 | LMNA (0.62) | LMNAALDH1A1MAPTSMN1; SMN2PGR | |
| SCHEMBL9498632 | 0.93 | LMNA (0.56) | LMNAALDH1A1MAPTSMN1; SMN2PGR | |
| SCHEMBL1607138 | 0.89 | LMNA (0.75) | LMNAALDH1A1MAPTSMN1; SMN2PGR | |
| SCHEMBL8186503 | 0.83 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTSMN1; SMN2CHRNA7 | |
| SCHEMBL29861210 | 0.82 | LMNA (0.65) | LMNAALDH1A1MAPTSMN1; SMN2PGR | |
| SCHEMBL540784 | 0.81 | ALDH1A1 (0.42) | LMNAALDH1A1MAPTSMN1; SMN2CHRNA7 | |
| SCHEMBL13965237 | 0.81 | LMNA (0.42) | LMNAALDH1A1MAPTSMN1; SMN2PGR | |
| SCHEMBL6134241 | 0.80 | TSHR (0.46) | LMNAALDH1A1MAPTSMN1; SMN2CHRNA7 | |
| SCHEMBL12610437 | 0.80 | ESR1 (0.62) | LMNAALDH1A1MAPTSMN1; SMN2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955244-A | Method for preparing primary alcohol by homogeneously catalyzing and reducing carboxylic acid derivative by using N-heterocyclic carbene copper complex | 延安大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-118344371-A | Azaspiro compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2024-07-16 | — | — | CN | disclosed |
| EP-3397629-B1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2023-04-19 | — | — | EP | disclosed |
| CN-115896187-A | Method for preparing prochiral ketone compound by biological oxidation through continuous flow device | 南京工业大学 | 2023-04-04 | — | — | CN | disclosed |
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-07-14 | — | — | US | disclosed |
| CN-113613494-A | Fungicidal arylamidines | 科迪华农业科技有限责任公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-108821931-B | Catalytic oxidation synthesis method of benzoic acid compound | 浙江工业大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-112165940-A | OX2R compound | 德克萨斯州立大学董事会 | 2021-01-01 | — | — | CN | disclosed |
| WO-2020237131-A1 | FUNGICIDAL ARYL AMIDINES | DOW AGROSCIENCES LLC (US) | 2020-11-26 | — | — | WO | disclosed |
| US-10335775-B2 | Magnetically separable iron-based heterogeneous catalysts for dehydrogenation of alcohols and amines | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-07-02 | — | — | US | disclosed |
| EP-0450995-B1 | New propanamines, their pharmacological properties and their therapeutical applications, notably as anti-diarrhoea agents | JOUVEINAL SA (FR) | 1994-06-08 | — | — | EP | disclosed |
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| EP-0523697-A1 | Color-developing compositions and their use | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-5143938-A | PROPANAMINES, THEIR PHARMACOLOGICAL PROPERTIES AND THEIR APPLICATION FOR THERAPEUTIC IN PARTICULAR ANTIDIARRHEAL, PURPOSES | JOUVEINAL S.A. (FR) | 1992-09-01 | — | — | US | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0450995-A1 | New propanamines, their pharmacological properties and their therapeutical applications, notably as anti-diarrhoea agents | JOUVEINAL S.A. (FR) | 1991-10-09 | — | — | EP | disclosed |
| US-5023366-A | Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-06-11 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |
| EP-0285880-A2 | Plant growth regulating agent | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | disclosed |
| EP-0268878-A2 | Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CYP1A1, CYP1A2, CYP1B1 | LMNA 3813/4885ALDH1A1 105/4885MAPT 4011/4885 |
| US-10335775-B2 | Magnetically separable iron-based heterogeneous catalysts for dehydrogenation of alcohols and amines | ADH1A, ADH1C, ADH5 | LMNA 2041/4885ALDH1A1 97/4885MAPT 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.