Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176207 | 0.81 | DGAT1 (0.34) | CYP2D6DGAT1NR1D1NR1H3HDAC1 | |
| SCHEMBL18510032 | 0.81 | DGAT1 (0.34) | CYP2D6DGAT1NR1D1HDAC1HDAC2 | |
| SCHEMBL27420033 | 0.78 | NR1D1 (0.38) | CYP2D6DGAT1NR1D1NR1H3HDAC1 | |
| SCHEMBL8861725 | 0.77 | CYP2D6 (0.33) | CYP2D6DGAT1NR1D1HDAC1HDAC2 | |
| SCHEMBL13676332 | 0.77 | CYP2D6 (0.33) | CYP2D6DGAT1NR1D1HDAC1HDAC2 | |
| SCHEMBL10661515 | 0.76 | DGAT1 (0.34) | CYP2D6DGAT1NR1D1NR1H3HDAC1 | |
| SCHEMBL1689401 | 0.76 | HDAC6 (0.37) | CYP2D6DGAT1HDAC1HDAC2HDAC6 | |
| SCHEMBL2803666 | 0.76 | GAA (0.35) | CYP2D6DGAT1NR1D1NR1H3HDAC1 | |
| SCHEMBL1966612 | 0.75 | ALDH1A1 (0.37) | HDAC1HDAC2HDAC6CA12CA1 | |
| SCHEMBL15548847 | 0.74 | NR1D1 (0.36) | CYP2D6DGAT1NR1D1NR1H3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179956-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS STAT5 INHIBITORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-12-03 | — | — | WO | disclosed |