Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.55 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.51 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384215 | 1.00 | PTGS1 (0.55) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL32670710 | 0.98 | PTGS1 (0.54) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL30903459 | 0.94 | GLO1 (0.50) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL3909775 | 0.92 | PTGS1 (0.54) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL13886471 | 0.92 | PTGS1 (0.54) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL18285487 | 0.91 | DPP4 (0.50) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL30618466 | 0.90 | GLO1 (0.49) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29693286 | 0.90 | GLO1 (0.49) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29526446 | 0.90 | PTGS1 (0.52) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29586584 | 0.90 | PTGS1 (0.53) | PTGS1GSTK1GLO1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058932-A1 | ACTIVE INGREDIENT-PEPTIDE CONSTRUCT FOR EXTRACELLULAR CONCENTRATION | MAX PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058932-A1 | ACTIVE INGREDIENT-PEPTIDE CONSTRUCT FOR EXTRACELLULAR CONCENTRATION | VIP, FIBP, MMP7 | PTGS1 1350/4885GSTK1 4485/4885GLO1 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.