SCHEMBL18285487

SCHEMBL18285487

CCC[C@H](NC(=O)[C@@H](N)CCC(=O)O)C(=O)NCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.50
DPP8 Q6V1X1 3/20 0.50
DPP9 Q86TI2 3/20 0.50
PTGS1 P23219 1/20 0.50
GSTK1 Q9Y2Q3 1/20 0.50
GLO1 Q04760 1/20 0.50
ALDH1A1 P00352 2/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GSR P00390 1/20 0.41
CYP1A2 P05177 1/20 0.41
GRIK1 P39086 1/20 0.41
GRM5 P41594 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18285492 0.92 GLO1 (0.48) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL29384215 0.91 PTGS1 (0.55) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL173099 0.91 PTGS1 (0.55) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL30712618 0.90 DPP4 (0.51) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL32670710 0.89 PTGS1 (0.54) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL13886471 0.86 PTGS1 (0.54) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL3909775 0.86 PTGS1 (0.54) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL30903459 0.85 GLO1 (0.50) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL29526446 0.85 PTGS1 (0.52) DPP4DPP8DPP9PTGS1GSTK1
SCHEMBL8495650 0.84 DPP4 (0.55) DPP4DPP8DPP9GRM8GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES OSMO LABS PBC (US) 2026-01-29 US disclosed
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS, PBC 2025-10-09 US disclosed
US-20250234910-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES OSMO LABS, PBC 2025-07-24 US disclosed
US-20250236810-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING BENZENE DERIVATIVES OSMO LABS, PBC 2025-07-24 US disclosed
WO-2025049824-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES OSMO LABS, PBC (US) 2025-03-06 WO disclosed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US disclosed
WO-2025049827-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING PYRAZOLE DERIVATIVES OSMO LABS, PBC (US) 2025-03-06 WO disclosed
US-20240376038-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING HYDROXYMELONAL FORMATE ESTER P2 SCIENCE INC (US) 2024-11-14 US disclosed
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
US-20180163158-A1 OLFACTIVE COMPOSITIONS COMPRISING CYCLOHEXYL-ALKYL CARBINOLS P2 SCIENCE, INC. 2018-06-14 US disclosed
EP-3303534-A1 OLFACTIVE COMPOSITIONS COMPRISING CYCLOHEXYL-ALKYL CARBINOLS P2 Science, Inc. (US) 2018-04-11 EP disclosed
US-20180037844-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEOPENTYL GLYCOL DIACETATE P2 SCIENCE, INC. 2018-02-08 US disclosed
US-9732071-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2017-08-15 US disclosed
US-20170119032-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED 2017-05-04 US disclosed
WO-2017075257-A2 HIGH INTENSITY SWEETENERS SENOMYX, INC. (US) 2017-05-04 WO disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 US disclosed
WO-2016197000-A1 OLFACTIVE COMPOSITIONS COMPRISING CYCLOHEXYL-ALKYL CARBINOLS P2 SCIENCE, INC. (US) 2016-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170119032-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 DPP4 743/4885DPP8 1035/4885DPP9 924/4885
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CYP8B1, CYP1B1, BBOX1 DPP4 4841/4885DPP8 3466/4885DPP9 4570/4885
US-20180163158-A1 OLFACTIVE COMPOSITIONS COMPRISING CYCLOHEXYL-ALKYL CARBINOLS ACMSD, TAS2R1, MINK1 DPP4 3919/4885DPP8 3878/4885DPP9 3909/4885
US-20240376038-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING HYDROXYMELONAL FORMATE ESTER ADH5, HTR5A, FAAH DPP4 4176/4885DPP8 4416/4885DPP9 3697/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 DPP4 2533/4885DPP8 2465/4885DPP9 2106/4885
US-20250236810-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING BENZENE DERIVATIVES BBOX1, NISCH, TAS2R4 DPP4 1804/4885DPP8 2636/4885DPP9 3294/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D DPP4 1291/4885DPP8 1545/4885DPP9 897/4885
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES TAS2R42, TAS2R4, TAS2R41 DPP4 2463/4885DPP8 3423/4885DPP9 3987/4885
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 DPP4 4882/4885DPP8 4651/4885DPP9 4873/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 DPP4 3386/4885DPP8 322/4885DPP9 2861/4885
US-20250234910-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES TAS1R3, TAS2R5, TRPA1 DPP4 2183/4885DPP8 2357/4885DPP9 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.