Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | INSR | P06213 | 3/20 | 0.57 |
| ▸ | APP | P05067 | 5/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29105316 | 0.99 | KMT2A (0.69) | KMT2AHTTMEN1POLBALDH1A1 | |
| Bromide SCHEMBL17311237 | 0.89 | KMT2A (0.56) | KMT2AHTTMEN1POLBALDH1A1 | |
| SCHEMBL17325581 | 0.87 | KMT2A (0.57) | KMT2AHTTMEN1POLBALDH1A1 | |
| SCHEMBL13005219 | 0.86 | INSR (0.64) | KMT2AHTTMEN1POLBALDH1A1 | |
| Bromide SCHEMBL17311238 | 0.85 | INSR (0.57) | KMT2AHTTMEN1POLBALDH1A1 | |
| SCHEMBL12880678 | 0.81 | INSR (0.63) | KMT2AHTTMEN1POLBALDH1A1 | |
| SCHEMBL12880679 | 0.80 | INSR (0.62) | KMT2AHTTMEN1POLBALDH1A1 | |
| SCHEMBL34468132 | 0.80 | INSR (0.72) | KMT2AHTTMEN1ALDH1A1PKM | |
| Iodide SCHEMBL12470899 | 0.78 | INSR (0.70) | KMT2AHTTMEN1ALDH1A1PKM | |
| Bromide SCHEMBL17311242 | 0.78 | MEN1 (0.55) | KMT2AHTTMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150353515-A1 | Novel analogs of resveratrol | HUANG WEN-HSIN (TW) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353515-A1 | Novel analogs of resveratrol | KDR, FLT1, SIRT1 | KMT2A 2792/4885HTT 1440/4885MEN1 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.