Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL5966733 | 1.00 | SLC34A1 (0.40) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL28747654 | 1.00 | SLC34A1 (0.40) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL8762220 | 1.00 | SLC34A1 (0.40) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL8762325 | 1.00 | SLC34A1 (0.40) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL728737 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL11097300 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL9511742 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL3836363 | 0.96 | LMNA (0.35) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL2561285 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL36336 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107072896-A | Oral care composition containing zinc salt and calcium carbonate | 高露洁-棕榄公司 | 2017-08-18 | — | — | CN | claimed |
| US-9650509-B2 | Polycarbonate resin composition | LG CHEM, LTD. (KR) | 2017-05-16 | — | — | US | disclosed |
| US-20150353727-A1 | POLYCARBONATE RESIN COMPOSITION | LG CHEM, LTD. (KR) | 2015-12-10 | — | — | US | disclosed |