Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL8762220

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nearest known ligand 0.40

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.40
CA1 P00915 2/20 0.33
CA4 P22748 2/20 0.33
CA5A P35218 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL17315007 1.00 SLC34A1 (0.40) SLC34A1CA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL5966733 1.00 SLC34A1 (0.40) SLC34A1CA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL28747654 1.00 SLC34A1 (0.40) SLC34A1CA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL8762325 1.00 SLC34A1 (0.40) SLC34A1CA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL728737 0.96 SLC34A1 (0.43) SLC34A1CA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL11097300 0.96 SLC34A1 (0.43) SLC34A1CA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL9511742 0.96 SLC34A1 (0.43) SLC34A1CA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL3836363 0.96 LMNA (0.35) SLC34A1CA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL2561285 0.96 SLC34A1 (0.43) SLC34A1CA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL36336 0.96 SLC34A1 (0.43) SLC34A1CA1CA4CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502504-B1 A biosensor utilizing enzyme and a method for producing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1997-07-02 EP claimed
US-5192415-A Biosensor utilizing enzyme and a method for producing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-03-09 US claimed
EP-0502504-A1 A biosensor utilizing enzyme and a method for producing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-09-09 EP claimed
EP-0502504-B1 A biosensor utilizing enzyme and a method for producing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1997-07-02 EP disclosed
US-5192415-A Biosensor utilizing enzyme and a method for producing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-03-09 US disclosed
EP-0502504-A1 A biosensor utilizing enzyme and a method for producing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-09-09 EP disclosed