Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19097302 | 0.99 | HTR2C (0.52) | HTR2CHTR2BGRIA2HTR7HTR2A | |
| SCHEMBL17317603 | 0.91 | HTR7 (0.51) | HTR2CHTR2BGRIA2HTR7HTR2A | |
| SCHEMBL17317842 | 0.90 | GRIA2 (0.45) | HTR2CHTR2BGRIA2HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL17317784 | 0.89 | GRIA2 (0.44) | HTR2CHTR2BGRIA2HTR7HTR2A | |
| SCHEMBL17317536 | 0.89 | GRIA2 (0.46) | HTR2CHTR2BGRIA2HTR7HTR2A | |
| SCHEMBL17317624 | 0.89 | HTR7 (0.54) | HTR2CHTR2BGRIA2HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL19097267 | 0.88 | GRIA2 (0.46) | HTR2CHTR2BGRIA2HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL19097303 | 0.88 | HTR7 (0.53) | HTR2CHTR2BGRIA2HTR7HTR2A | |
| SCHEMBL17317891 | 0.86 | SMN1; SMN2 (0.49) | HTR2CHTR2BGRIA2HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL19097258 | 0.85 | SMN1; SMN2 (0.48) | HTR2CHTR2BGRIA2HTR7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. | 2017-07-13 | — | — | US | disclosed |
| EP-3152206-A1 | ATX MODULATING AGENTS | Biogen MA Inc. (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015188051-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. (US) | 2015-12-10 | — | — | WO | disclosed |
| WO-2015188051-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. (US) | 2015-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | ENPP2, ATXN10, ATXN2 | HTR2C 1020/4885HTR2B 343/4885GRIA2 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.