Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.73 |
| ▸ | TP53 | P04637 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130403 | 0.82 | KDM4E (0.73) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL3128145 | 0.80 | ALDH1A1 (0.67) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL13757050 | 0.78 | ALDH1A1 (0.68) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL3124699 | 0.78 | ALDH1A1 (0.77) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL3134218 | 0.78 | ALDH1A1 (0.68) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL3130399 | 0.78 | MAPT (0.66) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL3133866 | 0.77 | ALDH1A1 (0.67) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL3125211 | 0.77 | ALDH1A1 (0.63) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL3910984 | 0.76 | MAPT (0.60) | MAPTTP53KDM4EHPGDALDH1A1 | |
| SCHEMBL3131662 | 0.76 | MAPT (0.62) | MAPTTP53KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015187827-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2015-12-10 | — | — | WO | disclosed |