Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17319367 | 0.82 | SLC6A4 (0.46) | AKR1C3AKR1C2LMNAMEN1KMT2A | |
| SCHEMBL17319354 | 0.80 | LMNA (0.43) | LMNASMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL14966813 | 0.78 | FFAR1 (0.46) | AKR1C3AKR1C2LMNAMEN1KMT2A | |
| SCHEMBL8282434 | 0.77 | AKR1C2 (0.43) | AKR1C3AKR1C2LMNAMEN1HTT | |
| SCHEMBL17319365 | 0.76 | SLC6A4 (0.49) | MEN1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL14966937 | 0.75 | TSHR (0.47) | AKR1C3AKR1C2LMNAMEN1KMT2A | |
| SCHEMBL4363303 | 0.73 | FFAR1 (0.56) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL18703603 | 0.73 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1IGLV6-57ALOX5 | |
| SCHEMBL19193471 | 0.73 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1IGLV6-57ALOX5 | |
| SCHEMBL14966858 | 0.73 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1IGLV6-57ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206128-B2 | Modulators of methyl modifying enzymes, compositions and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2015-12-08 | — | — | US | disclosed |