Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320889 | 0.88 | MAPT (0.49) | CA1CA2MAPTMAPK1HIF1A | |
| SCHEMBL24346426 | 0.85 | HTT (0.46) | CA1CA2MAPTMAPK1HIF1A | |
| SCHEMBL13820249 | 0.83 | CA1 (0.58) | CA1CA2MAPTMAPK1HSD17B10 | |
| SCHEMBL26324657 | 0.79 | HPGD (0.49) | CA1CA2MAPTTP53SMN1; SMN2 | |
| SCHEMBL15982271 | 0.76 | KMT2A (0.63) | MAPTMAPK1HIF1AHSD17B10TP53 | |
| SCHEMBL13523477 | 0.75 | CA1 (0.46) | CA1CA2TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL11147135 | 0.74 | CA1 (0.72) | CA1CA2MAPTMAPK1NFKB1 | |
| SCHEMBL11147132 | 0.74 | CA1 (0.72) | CA1CA2MAPTMAPK1NFKB1 | |
| SCHEMBL17773308 | 0.73 | MAPT (0.58) | CA2MAPTMAPK1HSD17B10KDM4E | |
| SCHEMBL21787273 | 0.73 | NME4 (0.40) | CA1CA2MAPTHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10400024-B2 | Cleavage and exchange of major histocompatibility complex ligands employing azobenzene-containing peptides | SANQUIN REAGENTS B.V. (NL) | 2019-09-03 | — | — | US | disclosed |
| US-20170101459-A1 | CLEAVAGE AND EXCHANGE OF MAJOR HISTOCOMPATIBILITY COMPLEX LIGANDS EMPLOYING AZOBENZENE-CONTAINING PEPTIDES | STICHTING SANQUIN BLOEDVOORZIENING (NL) | 2017-04-13 | — | — | US | disclosed |
| WO-2015187019-A1 | CLEAVAGE AND EXCHANGE OF MAJOR HISTOCOMPATIBILITY COMPLEX LIGANDS EMPLOYING AZOBENZENE-CONTAINING PEPTIDES | STICHTING SANQUIN BLOEDVOORZIENING (NL) | 2015-12-10 | — | — | WO | disclosed |
| EP-2952520-A1 | Cleavage and exchange of major histocompatibility complex ligands employing azobenzene-containing peptides. | Stichting Sanquin Bloedvoorziening (NL) | 2015-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101459-A1 | CLEAVAGE AND EXCHANGE OF MAJOR HISTOCOMPATIBILITY COMPLEX LIGANDS EMPLOYING AZOBENZENE-CONTAINING PEPTIDES | CD74, HLA-B, MICA | CA1 942/4885CA2 3035/4885MAPT 4310/4885 |
| US-10400024-B2 | Cleavage and exchange of major histocompatibility complex ligands employing azobenzene-containing peptides | CD74, HLA-B, MICA | CA1 942/4885CA2 3035/4885MAPT 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.